Sex lethal splicing

Sensory neurons in the uterus of female "D. As a result, individual genes express multiple mRNAs that are identical except for discrete regions of variability. The most important of all the pair rule genes are even skipped eve and Fushi tarazu ftz [but the primary pair rule genes are hairy and even skipped].



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Research has shown that they are active during the day but their level of movement decreases during the night, though it is not clear if this decrease is due to sleep or quiet waking Cirelli and Bushey, Though ds proteins sequestered, they are distributed all over the cytoplasm.


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Wing is a secreted protein acts as ligand on engrailed cells. The largest dynactin subunit, pGlued turquoise , forms an elongated dimer that interacts with the dynein intermediate chain and binds to microtubules via a highly conserved CAP-Gly motif at the tip of globular heads. There are extensive images at FlyBase.


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Mix-and-Match Critters

At low concentration of Ds factors at upper region of the ventro-lateral stretch, Ds activates Sogo genes in cells for their enhancer region consists of four high response Elements RE. There three major forms and they further vary; this is because of alternative splicing. What's with all the screaming? It has 95 alternative splice sites and 25 constitutive splicing sites and it has the potential to generate 38 different mRNAs and different proteins; this is an incredible achievement by neuronal cells.

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  1. Schematic drawing representing the genomic structure of the AM gene and the alternative splicing mechanism governing the differential expression of AM and PAMP.